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Systemic mastocytosis is characterized by an increased number of mast cells in multiple organs particularly skin.A 55-year-old man with mastocytosis presented with nyctalopia caused by malabsorption of vitamin A.Diagnosis was made by documenting a low vitamin A level and an ERG that showed rod-cone deficiency with rods affected more than cones.Vitamin A therapy led to return of good visual function.To our knowledge,this is the first reported case of mastocytosis induced nyctalopia.Vitamin A deficiency should be considered as a potential cause of visual loss in patients with sudden onset of night blindness. |
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